8/3/2023 0 Comments Poc bnp istatPoint-of-care INR testing is becoming increasingly popular in general practice for monitoring patients on warfarin therapy. Plasma creatinine measurement is currently the subject of an international standardisation, in which both laboratory and point-of-care testing methods are being aligned to an isotope dilution mass spectrometry reference method. Quantitative measurement of urine albumin or urine albumin–creatinine ratio is a key component in the review of patients with diabetes. However, they calculate the low density lipoprotein (LDL) cholesterol using the Friedewald formula and cannot, as yet, determine LDL cholesterol directly as laboratories can now do. Testing devices measure a full lipid profile on capillary or venous blood. Measuring blood lipids is useful for cardiovascular disease risk assessment and for managing patients on lipid lowering therapy. These generally measure whole blood glucose rather than plasma glucose, although newer devices can report a plasma-equivalent glucose concentration. There are numerous strip-based testing devices for glucose monitoring. Devices measure Hb A1c using either immunoassay or boronate affinity chromatography methods. Hb A1c remains the gold standard pathology test for long-term monitoring of glycaemic control in patients with diabetes. N-terminal pro b-type natriuretic peptide Point-of-care tests for chronic and acute care Some tests such as haemoglobin and INR have both chronic and acute applications. Table 1 lists examples of the more common biochemistry and haematological tests. Point-of-care tests (both singly and in profile) are now available for acute and chronic situations and can be used for example in managing diabetes, warfarin requirements, electrolyte and acid–base disturbances and risk stratification of patients with suspected acute coronary syndrome.
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